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[溃疡病中人类胃部微循环血管的变化]

[Changes in the microcirculatory vessels of the human stomach in ulcer disease].

作者信息

Popovich F A

出版信息

Arkh Anat Gistol Embriol. 1982 Sep;83(9):50-6.

PMID:7181696
Abstract

At the ulcerous disease certain alterations in the microcirculatory bed of all the gastric wall layers take place in the zone of the ulcer and in the areas adjoining the ulcerous focus. In the gastric wall areas, remote from the ulcer, the alterations in the microcirculatory bed are poorly manifested. The most essential deviations from the norm are defined in the mucosal tunic and in the gastric tela submucosa according to the ulcer localization. The disorders in the microcirculatory bed at the ulcerous disease affect the microarchitectonics, the wall structure and the size of the microvessel lumens and their contents. Maximal alterations are observed in capillaries and postcapillary-venular portion of the microcirculatory bed, which are manifested as a considerable dilatation of the microvessels mentioned, deformity, presence of rather great protrusions of their wall. The resistive vessels of the microcirculatory bed, at the ulcerous disease, suffer to a less extent. The morphometric data have stated certain decrease of their diameter when comparing to the norm. The adaptive apparatuses of the bloodflow regulation at the ulcerous disease are essentially altered, increasing number of the arteriolovenular anastomoses is noted in the gastric wall as compared to the norm.

摘要

在溃疡病中,溃疡区域及其周边区域的胃壁各层微循环床会发生某些改变。在远离溃疡的胃壁区域,微循环床的改变表现不明显。根据溃疡的定位,在黏膜层和胃黏膜下层可发现与正常情况最显著的偏差。溃疡病时微循环床的紊乱会影响微结构、胃壁结构以及微血管腔的大小及其内容物。在微循环床的毛细血管和毛细血管后微静脉部分观察到最大的改变,表现为上述微血管的显著扩张、变形以及其壁上出现相当大的突起。溃疡病时,微循环床的阻力血管受累程度较小。与正常情况相比,形态学数据表明其直径有所减小。溃疡病时血流调节的适应性装置发生了本质改变,与正常情况相比,胃壁中动静脉吻合支的数量增加。

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