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[直肠癌放疗前后血液及淋巴毛细血管的超微结构]

[Ultrastructure of blood and lymphatic capillaries of rectal cancer before and after irradiation].

作者信息

Zaretskaia A I, Lushnikov E F

出版信息

Arkh Patol. 1982;44(10):73-9.

PMID:7181712
Abstract

The ultrastructure of blood and lymph capillaries of rectal adenocarcinoma was studied before and after pre-operation radiation therapy. The walls of blood capillaries of the tumor were formed by endothelial cells, basal membrane, and pericytes, while those of lymph capillaries by endothelial cells alone. After irradiation of the tumor at a dose of 20 Gr the total architechtonics of the vessel wall of blood and lymph capillaries was retained, but the lumen of many capillaries became smaller, and connections between endotheliocytes weaker. Radiation changes of endothelial cells of the vessels of both types are similar and manifest as swelling, vacuolation of organelles of the cytoplasm, accumulation of lipid drops, distention of tubules and cisterns.

摘要

对直肠腺癌术前放疗前后的血液和淋巴毛细血管超微结构进行了研究。肿瘤的毛细血管壁由内皮细胞、基底膜和周细胞构成,而淋巴毛细血管壁仅由内皮细胞构成。肿瘤接受20戈瑞剂量的照射后,血液和淋巴毛细血管壁的整体结构得以保留,但许多毛细血管的管腔变小,内皮细胞之间的连接变弱。两种类型血管的内皮细胞辐射变化相似,表现为肿胀、细胞质细胞器空泡化、脂滴积聚、小管和池扩张。

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