Lokshin L S, Osipov V P, Knjazeva G, Rogov K A, Lepilin M G, Arseniev S B, Romanov V A, Leonova S A
Artif Organs. 1982 Aug;6(3):299-302. doi: 10.1111/j.1525-1594.1982.tb01676.x.
Mechanical support of the failing heart in the form of bypass of the left and right ventricles by roller pumps was used in 25 dogs with model cardiogenic shock. Early application of left ventricular bypass in acute heart failure normalizes the myocardial bioenergy state and promotes reversible changes in myocardial ultrastructure as demonstrated by an increased surface area of mitochondrial cristae. On the basis of hemodynamics and morphology, we conclude that pump-aided bypass of ventricles without synchronization is a simple and effective method of circulation assistance. Mechanical support duration from 1 to 138 hours has been used in 10 patients following corrective heart surgery.
在25只患有心源性休克模型的犬中，采用滚压泵对左、右心室进行旁路循环的方式对衰竭心脏进行机械支持。急性心力衰竭时早期应用左心室旁路循环可使心肌生物能量状态正常化，并促进心肌超微结构的可逆性改变，表现为线粒体嵴表面积增加。基于血流动力学和形态学，我们得出结论，非同步的心室泵辅助旁路循环是一种简单有效的循环辅助方法。10例心脏矫正手术后的患者接受了1至138小时的机械支持。
