Kemp J D, Stenn K S, Arons M, Fischer J
Arch Dermatol. 1978 Oct;114(10):1533-5. doi: 10.1001/archderm.114.10.1533.
Atypical fibroxanthoma (AFX) is one of a group of cutaneous lesions with a malignant histological appearance but a generally benign clinical course. A 79-year-old white man had AFX of the cheek that recurred and metastasized to buccal and cervical lymph nodes three months after initial diagnosis. When careful physical and and laboratory examinations were done, the patient was found to have concomitant chronic lymphatic leukemia, "null cell" type. In view of the low incidence of metastasizing AFX and the increased occurrence of tumors in patients with lymphomatous disorders, an important association is suggested. Before establishing the prognosis for patients with pseudomalignancies of the skin, an evaluation of their general health and immunological status should be made.
非典型纤维黄色瘤（AFX）是一组具有恶性组织学表现但临床过程通常为良性的皮肤病变之一。一名79岁的白人男性患有脸颊部的AFX，在初次诊断三个月后复发并转移至颊部和颈部淋巴结。在进行仔细的体格检查和实验室检查时，发现该患者同时患有“无细胞”型慢性淋巴细胞白血病。鉴于转移性AFX的低发病率以及淋巴瘤性疾病患者中肿瘤发生率的增加，提示存在重要关联。在确定皮肤假性恶性肿瘤患者的预后之前，应评估其总体健康状况和免疫状态。
