Brockbank K G, Piersma A H, Van Peer C M
Biomed Pharmacother. 1982;36(8-9):369-71.
The distribution of fibroblastoid colony-forming units (CFU-F) in mouse femoral marrow was investigated. Mechanically dispersed marginal and axial marrow fractions had the same CFU-F frequency. Metaphyseal marrow had a high CFU-F frequency in young (6 week) mice. Trypsinization of bone marrow fractions before mechanical dispersion resulted in an increased CFU-F plating efficiency and a higher incidence of CFU-F in marginal marrow (156 +/- 41%) than in axial marrow. The femoral marrow CFU-F distribution correlates with that expected on the basis of their role in both bone and marrow stroma formation.
研究了小鼠股骨骨髓中成纤维细胞样集落形成单位（CFU-F）的分布。机械分散的边缘和轴心骨髓部分具有相同的CFU-F频率。干骺端骨髓在年轻（6周龄）小鼠中具有较高的CFU-F频率。在机械分散之前对骨髓部分进行胰蛋白酶处理，导致CFU-F的接种效率提高，且边缘骨髓中CFU-F的发生率（156±41%）高于轴心骨髓。股骨骨髓CFU-F的分布与其在骨和骨髓基质形成中的作用所预期的分布相关。
