Geary D F, Fennell R S, Braylan R C, Iravani A, Garin E H, Richard G A
Eur J Pediatr. 1982 Dec;139(4):296-8. doi: 10.1007/BF00442185.
The clinical course of an adolescent on chronic hemodialysis with severe hyperparathyroidism, osteodystrophy and profound anemia is described. After 1,25,dihydroxycholecalciferol was instituted for therapy, bone disease improved as evidenced by radiographic findings. Transfusion requirements diminished and bone marrow fibrosis on serial biopsies decreased significantly. These therapeutic results link hyperparathyroidism with the pathogenesis of anemia in chronic renal failure.
本文描述了一名患有严重甲状旁腺功能亢进、骨营养不良和严重贫血的青少年慢性血液透析患者的临床病程。在开始使用1,25 - 二羟胆钙化醇进行治疗后，影像学检查结果表明骨病有所改善。输血需求减少，连续活检显示骨髓纤维化显著减轻。这些治疗结果表明甲状旁腺功能亢进与慢性肾衰竭贫血的发病机制有关。
