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草酸钙尿路结石的流行病学、发病机制与诊断

Epidemiology, Pathogenesis and diagnosis of calcium oxalate urolithiasis.

作者信息

Vahlensieck E W, Bach D, Hesse A, Strenge A

出版信息

Int Urol Nephrol. 1982;14(4):333-47. doi: 10.1007/BF02081972.

DOI:10.1007/BF02081972
PMID:7182367
Abstract

In the German Federal Republic, the incidence of urolithiasis is 0.54% and the prevalence is 4%. Calcium oxalate stones are to be expected in over 60% of the cases. Pathogenetic factors are discussed. It is demonstrated that the overconsumption of chocolate, rhubarb and spinach brings about risk situations for stone formation, while asparagus and tomatoes present no risk. The increased animal protein and alcohol intake may be the most important reasons for the accumulations of calcium oxalate stones. Beside the minimum investigation programme it is demonstrated by examples that recurrent stone formers need an extended investigation to find out more about the pathogenesis, in order to determine an effective treatment or to prevent recurrences.

摘要

在德意志联邦共和国,尿石症的发病率为0.54%,患病率为4%。超过60%的病例预计会出现草酸钙结石。文中讨论了发病因素。结果表明,过量食用巧克力、大黄和菠菜会引发结石形成的风险状况,而芦笋和西红柿则不存在风险。动物蛋白和酒精摄入量的增加可能是草酸钙结石形成的最重要原因。除了最低限度的检查项目外,通过实例表明,复发性结石患者需要进行更广泛的检查,以进一步了解发病机制,从而确定有效的治疗方法或预防复发。

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本文引用的文献

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