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结肠镜检查及含浸润性癌息肉的处理

Colonoscopy and the management of polyps containing invasive carcinoma.

作者信息

Coutsoftides T, Sivak M V, Benjamin S P, Jagelman D

出版信息

Ann Surg. 1978 Nov;188(5):638-41. doi: 10.1097/00000658-197811000-00009.

Abstract

Experiences with 565 colonoscopic polypectomies and 91 colonic and rectal resections containing infiltrating carcinoma in polyps are reviewed. A plan of management based on pathologic study of resected polyps is formulated to avoid further unnecessary surgery. It was concluded that: (1) Tubular adenomas containing invasive carcinomas have a low incidence of metastatic node involvement. This incidence is related to the depth of carcinomatous involvement. Resection of these polyps with a margin free of carcinoma constitutes definitive and adequate treatment and that (2) Villous adenomas containing invasive carcinoma have a high incidence of metastatic nodal involvement, and operative resection of the involved area of the colon is recommended, and that (3) Pedunculated tubulovillous adenomas containing invasive carcinoma behave like tubular adenomas, and the recommendations for further surgery in the patient with tubular adenomas with carcinoma apply equally well for these lesions. Sessile tubulovillous polyps tend to behave like villous adenomas, and if invasive carcinoma is demonstrated, further operation is recommended.

摘要

回顾了565例结肠镜息肉切除术以及91例包含息肉浸润癌的结肠和直肠切除术的经验。制定了基于切除息肉病理研究的管理方案,以避免进一步的不必要手术。得出以下结论:(1)含有浸润癌的管状腺瘤发生转移淋巴结受累的发生率较低。该发生率与癌浸润深度有关。切除这些无癌边缘的息肉构成了明确且充分的治疗,并且(2)含有浸润癌的绒毛状腺瘤发生转移淋巴结受累的发生率较高,建议对结肠受累区域进行手术切除,并且(3)含有浸润癌的有蒂管状绒毛状腺瘤的行为类似于管状腺瘤,对于患有管状腺瘤伴癌患者进一步手术的建议同样适用于这些病变。无蒂管状绒毛状息肉往往表现得像绒毛状腺瘤,如果证实存在浸润癌,则建议进一步手术。

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本文引用的文献

1
Diagnosis and treatment of adenomatous polyps of colon.结肠腺瘤性息肉的诊断与治疗
AMA Arch Surg. 1952 Jul;65(1):65-71. doi: 10.1001/archsurg.1952.01260020077006.
2
Carcinoma arising in adenomas of colon and rectum.发生于结肠和直肠腺瘤的癌。
J Am Med Assoc. 1952 Apr 26;148(17):1465-9. doi: 10.1001/jama.1952.02930170005002.
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The surgical treatment of malignant rectal polyps.恶性直肠息肉的外科治疗
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