Bower R J, Sieber W K, Kiesewetter W B
Ann Surg. 1978 Nov;188(5):669-74. doi: 10.1097/00000658-197811000-00015.
This report reviews the experience with 78 alimentary tract duplications found in 64 patients over a 40 year period at the Children's Hospital of Pittsburgh. Ten patients had the duplication discovered at autopsy. Multiple duplications were found in 15% of patients. The symptoms and physical findings of a duplication varied with location, size and mucosal pattern. About one-fifth of the duplications contained ectopic mucosa, usually gastric. Two-thirds of the patients were diagnosed prior to one year of age. Vertebral anomalies, as a clue to the presence of the lesion, were present in 15% of the patients. The most common indications for surgery included a mediastinal or abdominal mass, intestinal obstruction, and gastrointestinal bleeding. The results of surgery were favorable, with a mortality of 20%. Surgical complications accounted for six deaths, while four children died of severe associated anomalies. Three others died without surgical treatment, but with symptoms from the duplication.
本报告回顾了匹兹堡儿童医院在40年期间对64例患者发现的78例消化道重复畸形的治疗经验。10例患者的重复畸形在尸检时发现。15%的患者存在多个重复畸形。重复畸形的症状和体格检查结果因位置、大小和黏膜形态而异。约五分之一的重复畸形含有异位黏膜,通常为胃黏膜。三分之二的患者在1岁前被诊断。15%的患者存在椎体异常,可作为病变存在的线索。最常见的手术指征包括纵隔或腹部肿块、肠梗阻和胃肠道出血。手术结果良好,死亡率为20%。手术并发症导致6例死亡,而4例儿童死于严重的相关畸形。另外3例未接受手术治疗,但因重复畸形出现症状而死亡。