原发性婴幼儿型青光眼（小梁发育异常）中前房角切开术的预后
Prognosis of goniotomy in primary infantile glaucoma (trabeculodysgenesis).
作者信息
Shaffer R N
出版信息
Trans Am Ophthalmol Soc. 1982;80:321-5.
In developmental glaucoma with trabeculodysgenesis (primary infantile glaucoma), goniotomy is a safe and highly successful operation and should be used in preference to trabeculotomy. Prognosis varies markedly with the age of onset of signs and symptoms. When present at birth or after the age of two years, the success rate is only about 30%. Between the ages of 1 and 24 months, success following one or two goniotomies is 94%. Eyes with successful goniotomies have now been followed for over 25 years with maintenance of pressure control without medication in most cases. The major complication has been amblyopia due to breaks in Descemet's membrane in the visual axis and to marked astigmatism and anisometropia. After 15 years, two cases developed an endothelial dystrophy and three had an IOP elevation. Obviously, periodic examination of such eyes will be necessary for life.
在伴有小梁发育异常的发育性青光眼（原发性婴幼儿青光眼）中，前房角切开术是一种安全且成功率很高的手术，应优先于小梁切开术使用。预后因体征和症状出现的年龄而有显著差异。若在出生时或两岁之后出现，成功率仅约为30%。在1至24个月龄之间，进行一或两次前房角切开术后的成功率为94%。现已对接受成功前房角切开术的眼睛进行了超过25年的随访，大多数情况下无需药物治疗即可维持眼压控制。主要并发症是由于视轴上的Descemet膜破裂以及明显的散光和屈光参差导致的弱视。15年后，有两例发生了内皮营养不良，三例眼压升高。显然，此类眼睛需要终身定期检查。
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