Department of Glaucoma, Biratnagar Eye Hospital, Biratnagar, Nepal.
Department of Ophthalmology, Gandaki Medical College and Teaching Hospital, Pokhara, Nepal.
JNMA J Nepal Med Assoc. 2021 Sep 11;59(241):867-870. doi: 10.31729/jnma.5889.
Primary congenital glaucoma is a rare vision-threatening condition of children. Primary congenital glaucoma though a rare disease it is the most common cause of childhood glaucoma with potency to cause blindness. This study was undertaken to find the prevalence of the children with primary congenital glaucoma under 3 years of age in a tertiary care hospital.
This was a descriptive cross-sectional study conducted at a tertiary eye center in Nepal in children (≤ 3 years) presented in the outpatient department of a tertiary eye hospital between June 2017 and June 2020. The study was approved by the hospital review committee and adhered to the declaration of Helsinki. A convenient sampling method was used. Point estimate at 95% Confidence Interval was calculated with frequency distribution. Data analysis was conducted using Statistical Package for the Social Sciences.
Out of total children under 3 years who presented to the outpatient department, 46 (0.31%) at 95% Confidence Interval (0.30-0.32) had primary congenital glaucoma. Among them, 30 children (65.2%) had bilateral involvement. Mean intraocular pressure was 42.40±8.15mm Hg. The mean age of initial presentation, horizontal corneal diameter, and axial length were 12.07±8.9 months, 12.95±1mm, and 23.89±1.7mm respectively. Consanguinity was observed in 12 (26%) children.
From the study, we conclude that there was a low prevalence of primary congenital glaucoma among children under 3 years of age who presented to the outpatient department in a tertiary care hospital.
原发性先天性青光眼是一种罕见的儿童致盲性眼病。虽然原发性先天性青光眼是一种罕见疾病,但它是儿童青光眼的最常见原因,有可能导致失明。本研究旨在探讨三级保健医院 3 岁以下儿童原发性先天性青光眼的患病率。
这是一项在尼泊尔一家三级眼科中心进行的描述性横断面研究,纳入 2017 年 6 月至 2020 年 6 月期间在一家三级眼科医院门诊就诊的(≤ 3 岁)儿童。本研究得到了医院审查委员会的批准,并遵循了赫尔辛基宣言。采用便利抽样法。用频率分布计算 95%置信区间的点估计值。使用社会科学统计软件进行数据分析。
在 3 岁以下就诊于门诊的儿童中,共有 46 例(0.31%),95%置信区间为(0.30-0.32)患有原发性先天性青光眼。其中,30 例(65.2%)为双眼受累。平均眼压为 42.40±8.15mmHg。首次就诊时的平均年龄、水平角膜直径和眼轴长度分别为 12.07±8.9 个月、12.95±1mm 和 23.89±1.7mm。12 例(26%)儿童有血缘关系。
本研究表明,在三级保健医院就诊的 3 岁以下儿童中,原发性先天性青光眼的患病率较低。