Ishimura K, Okamoto H, Fujita H
Arch Histol Jpn. 1978 Apr;41(2):187-93. doi: 10.1679/aohc1950.41.187.
The capillary endothelial pores of perfusion-fixed and immersion-fixed liver, thyroid and adrenal of mice were observed using freeze-etching preparations. In liver sinusoids, endothelial pores are heterogeneous in size and range from 50-100 nm. When the pores are classified into three types according to their size, small pores up to 100 nm in diameter represent 69.8%, intermediate pores measuring 100-500 nm 27.6% and large pores exceeding 500nm 2.6% of all pores in number. The endothelial pores of the thyroid blood capillaries are fairly homogeneous in size (70-90 nm), corresponding to the small type pores in the liver. In both adrenal cortex and medulla, the capillary endothelial pores measure 40-50 nm in diameter, showing small and intermediate types. In the adrenal cortex the former occupy 80.6% of all pores and the latter 19.4%. No larger type pores are recognized in the adrenal gland. These findings are not affected by different fixation methods, either perfusion or immersion.
采用冷冻蚀刻标本观察了灌注固定和浸入固定的小鼠肝脏、甲状腺及肾上腺的毛细血管内皮孔。肝血窦内的内皮孔大小不均一，范围为50 - 100nm。若按大小将这些孔分为三种类型，则直径达100nm的小孔占所有孔数量的69.8%，直径为100 - 500nm的中等大小孔占27.6%，直径超过500nm的大孔占2.6%。甲状腺毛细血管的内皮孔大小相当均一（70 - 90nm），相当于肝脏中的小类型孔。在肾上腺皮质和髓质中，毛细血管内皮孔直径为40 - 50nm，呈现小类型和中等类型。在肾上腺皮质中，前者占所有孔的80.6%，后者占19.4%。在肾上腺中未发现更大类型的孔。这些发现不受灌注或浸入等不同固定方法的影响。
