Kobayashi S, Goto K, Kano K
Arch Histol Jpn. 1978 Jun;41(3):285-90. doi: 10.1679/aohc1950.41.285.
Radioactivity in adrenal medullary chromaffin cells of the mouse was examined by autoradiographic methods 15 min to 1 hr after an intraperitoneal injection of 3H-dopa. In the normal control mice, the concentration of radioactivity was significantly higher in the A cells than in the NA cells, whereas in the hypophysectomized mice (9 days after operation by the transauricular method) the radioactivity was evenly distributed in the two cell types. It was suggested that both A and NA cells possessed a special trapping and concentrating mechanism for extracellular dopa and/or its metabolites and that the activity of this mechanism was made greater in the A cells than in the NA cells by the pituitary gland.
通过放射自显影法检测了腹腔注射3H-多巴后15分钟至1小时小鼠肾上腺髓质嗜铬细胞中的放射性。在正常对照小鼠中，A细胞中的放射性浓度显著高于NA细胞，而在垂体切除的小鼠（经耳后法手术后9天）中，放射性在这两种细胞类型中均匀分布。这表明A细胞和NA细胞都具有一种特殊的摄取和浓缩细胞外多巴和/或其代谢产物的机制，并且垂体使A细胞中该机制的活性比NA细胞中的更高。
