雌激素对骨代谢的影响。

The influence of oestrogen on bone metabolism.

作者信息

Langeland N

出版信息

Arch Orthop Trauma Surg (1978). 1978 Aug 30;92(2-3):149-52. doi: 10.1007/BF00397951.

Abstract

The literature concerning the effect of oestrogen upon bone metabolism is reviewed. Studies both in man and in laboratory animals have been considered. It is concluded that the most constant effect of oestrogen upon bone in man and most other mammals is reduced bone resorption. However, in man and most mammals the bone accretion rate is also reduced as a result of oestrogen influence. Previous studies reporting stimulated bone synthesis produced by oestrogen seem to be unreliable in the light of research of recent years. Thus oestrogen seem to produce an overall slow-down of bone metabolism.

摘要

本文综述了有关雌激素对骨代谢影响的文献。研究涵盖了人类和实验动物。结论是，雌激素对人类和大多数其他哺乳动物骨骼最持续的影响是减少骨吸收。然而，在人类和大多数哺乳动物中，由于雌激素的影响，骨生长率也会降低。根据近年来的研究，以前报道雌激素刺激骨合成的研究似乎并不可靠。因此，雌激素似乎会导致骨代谢整体减缓。