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[乙型肝炎病毒感染中的IgM/乙肝表面抗原复合物]

[IgM/HBsAG complexes in hepatitis B virus infections].

作者信息

Almi P, Fanetti G, Toti M, Rubino M

出版信息

Quad Sclavo Diagn. 1982 Sep;18(3):340-4.

PMID:7184047
Abstract

Sera from seventy patients suffering for HBsAg positive hepatitis, twenty-five HBsAg blood-donors, and eighty-four healthy subjects with no history of hepatitis, negative for all markers of HBV infection, were tested for circulating IgM/HBsAg complexes by a radioimmunoassay. IgM/HBsAg complexes, present in acute hepatitis patients at admission, progressively decreased and could not be demonstrated in sera of the convalescent phase. No complexes were found in sera from subjects negative for HBV markers. The results obtained from sera from HBsAg positive blood donors are compared with HBeAg/anti-HBe system. The absence of IgM/HBsAg complexes seems to be a sign of good prognosis in HBV infection.

摘要

采用放射免疫分析法对70例患乙肝表面抗原(HBsAg)阳性肝炎的患者、25例HBsAg献血者以及84例无肝炎病史且乙肝病毒(HBV)感染所有标志物均为阴性的健康受试者的血清进行循环免疫球蛋白M(IgM)/HBsAg复合物检测。急性肝炎患者入院时存在的IgM/HBsAg复合物逐渐减少,在恢复期血清中无法检测到。HBV标志物阴性的受试者血清中未发现复合物。将HBsAg阳性献血者血清的检测结果与乙肝e抗原(HBeAg)/乙肝e抗体(anti - HBe)系统的结果进行比较。IgM/HBsAg复合物的缺失似乎是HBV感染预后良好的一个标志。

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