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用于正热负荷的人体体温调节系统模型。

The model of human thermoregulatory system for positive heat loads.

作者信息

Grucza R

出版信息

Acta Physiol Pol. 1982 Jul-Aug;33(4):305-15.

PMID:7184314
Abstract

Body heat balance was calculated in men subjected to endogenous or exogenous heat load in order to test whether the human thermoregulatory system may be regarded as a servomechanism of heat exchange. Two series of experiments were carried out with male volunteers. In series I fifteen subjects performed 60 min physical exercise (at 50% V O2 max) at a constant ambient temperature of 25 degrees C. In series II sixteen subjects rested in a climatic chamber where the ambient temperature was increasing during 30 min from 22 to 42 degrees C and kept stable at this high level during subsequent 60 min. It was found, that in both series of experiments the sweating rate followed an exponential curve exhibiting an inertial course. The heat was stored in the body mainly at the beginning of experiments. It is concluded, that under the present experimental conditions, the heat loss from the body by sweat evaporation seems to be a regulated variable in the human thermoregulatory system. According to this conclusion the model of human thermoregulatory system acting as a servomechanism is proposed. In this model the "set-point" concept is unnecessary.

摘要

为了测试人类体温调节系统是否可被视为热交换的伺服机制,对处于内源性或外源性热负荷下的男性进行了体温平衡计算。对男性志愿者进行了两组实验。在第一组实验中,15名受试者在25摄氏度的恒定环境温度下进行了60分钟的体育锻炼(在最大摄氧量的50%)。在第二组实验中,16名受试者在气候舱中休息,环境温度在30分钟内从22摄氏度升至42摄氏度,并在随后的60分钟内保持在这个高水平稳定状态。结果发现,在两组实验中,出汗率均遵循呈惯性过程的指数曲线。热量主要在实验开始时储存在体内。得出的结论是,在目前的实验条件下,人体通过汗液蒸发散热似乎是人类体温调节系统中的一个调节变量。根据这一结论,提出了将人类体温调节系统作为伺服机制的模型。在这个模型中,“设定点”概念是不必要的。

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