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[胆囊和胆管癌的治疗]

[Treatment of cancer of the gallbladder and bile duct].

作者信息

Koga A, Nakayama F

出版信息

Gan To Kagaku Ryoho. 1982 Sep;9(9):1526-33.

PMID:7184460
Abstract

The records of 166 patients (85 men and 81 women) with extrahepatic bile duct cancers consisted of 58 patients with gallbladder cancer, 76 patients with bile duct cancer, and 32 patients with cancer of the papilla of vater were reviewed. A mean age was 60 years old (ranged: 30-80 years old). Twelve of 58 patients with gallbladder cancer were treated with simple cholecystectomy or extended cholecystectomy. Remaining 46 patients were treated with palliative treatments. The longest survival time of the resected patients was 3 1/2 years. Mean survival time of patients with palliative treatments was 5.6 months in external biliary drainage and 2.2 months in internal drainage. Thirteen of 76 patients with bile duct cancer were treated with bile duct resection or pancreatoduodenectomy. Remaining 63 patients were treated palliatively. Resectability rate was 10% in upper bile duct, 33% in middle and 36% in lower bile duct. The longest survival time was 3 1/2 years in upper bile duct, 2 2/3 years in middle and 3 5/6 in lower bile duct. Mean survival time of palliative treatments was 5.4 months in external drainage and 8.4 months in internal drainage. Twenty two of 32 patients with cancer of the papilla of Vater were treated with pancreatoduodenectomy. Remaining 10 patients received palliative treatments. The longest survival time was 11 years and 5 year survival rate was 14%. The longest survival time of the palliative treatments was 3 3/4 years and mean survival time was 14.2 months. To improve the resectability and operative results, early diagnosis and extended radical resection are necessary.

摘要

回顾了166例肝外胆管癌患者(85例男性和81例女性)的记录,其中包括58例胆囊癌患者、76例胆管癌患者和32例 Vater 壶腹癌患者。平均年龄为60岁(范围:30 - 80岁)。58例胆囊癌患者中有12例接受了单纯胆囊切除术或扩大胆囊切除术。其余46例患者接受了姑息治疗。接受切除手术患者的最长生存时间为3年半。接受姑息治疗的患者在外引流时平均生存时间为5.6个月,在内引流时为2.2个月。76例胆管癌患者中有13例接受了胆管切除术或胰十二指肠切除术。其余63例患者接受了姑息治疗。上段胆管的可切除率为10%,中段为33%,下段为36%。上段胆管的最长生存时间为3年半,中段为2年2/3,下段为3年5/6。姑息治疗的平均生存时间在外引流时为5.4个月,在内引流时为8.4个月。32例 Vater 壶腹癌患者中有22例接受了胰十二指肠切除术。其余10例患者接受了姑息治疗。最长生存时间为11年,5年生存率为14%。姑息治疗的最长生存时间为3年3/4,平均生存时间为14.2个月。为提高可切除率和手术效果,早期诊断和扩大根治性切除是必要的。

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