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[胆胰癌手术治疗后的远期结果]

[Late results after operative treatment of biliopancreatic cancer].

作者信息

Schramm H, Theilig K, Schmidt S, Arnold F

机构信息

Departement für Allgemein-, Viszeral- und Kinderchirurgie des Chirurgischen Zentrums der Wald-Klinikum gGmbH Gera.

出版信息

Zentralbl Chir. 2003 May;128(5):401-5. doi: 10.1055/s-2003-40036.

Abstract

In this paper the late results after operative therapy of biliopancreatic carcinomas will be presented. Tumors of this region have many things in common. That's why we investigated the 4 tumor entities together. We studied the case histories of 434 patients treated between 1981 and 1997. We analysed the in- and outpatient data of the "Klinikum der Stadt Gera", documents of the tumor board and informations that were obtained from the ambulatory treating physicians. 283 patients suffered from pancreatic carcinoma, 50 from bile duct carcinoma, 60 from gallbladder carcinoma and 41 from carcinoma of the papilla Vateri. The survival rates after curative or palliative operative therapy of the 4 tumor entities were calculated according to Kaplan-Meier. The rate of curative operations and the 5-year-survival-rate after curative resection were 32.8% and 19.0%, resp. in pancreatic carcinoma, 28.0% and 49.0% in bile duct carcinoma, 26.7% and 50.0% in gallbladder carcinoma and 71.0% and 44.0% in carcinoma of the papilla Vateri. Due to the higher resection rate the overall results in patients with carcinoma of the papilla Vateri were much better than the results in the other analysed cancers. Up to now resection is the only way to cure the 4 entities of malignant tumors of the biliopancreatic region.

摘要

本文将呈现胆胰癌手术治疗后的远期结果。该区域的肿瘤有许多共同之处。这就是我们将这4种肿瘤实体一并研究的原因。我们研究了1981年至1997年间接受治疗的434例患者的病历。我们分析了“ Gera市立医院”的门诊和住院数据、肿瘤委员会的文件以及从门诊治疗医生那里获得的信息。283例患者患有胰腺癌,50例患有胆管癌,60例患有胆囊癌,41例患有 Vater壶腹癌。根据Kaplan-Meier法计算了这4种肿瘤实体在根治性或姑息性手术治疗后的生存率。胰腺癌根治性手术率和根治性切除术后的5年生存率分别为32.8%和19.0%;胆管癌分别为28.0%和49.0%;胆囊癌分别为26.7%和50.0%;Vater壶腹癌分别为71.0%和44.0%。由于Vater壶腹癌的切除率较高,其总体结果远优于其他分析的癌症。到目前为止,手术切除是治愈胆胰区域4种恶性肿瘤实体的唯一方法。

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