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强直性肌营养不良中的周围神经病变。与葡萄糖不耐受的关系。

Peripheral neuropathy in myotonic dystrophy. Relation to glucose intolerance.

作者信息

Olson N D, Jou M F, Quast J E, Nuttall F Q

出版信息

Arch Neurol. 1978 Nov;35(11):741-5. doi: 10.1001/archneur.1978.00500350045009.

DOI:10.1001/archneur.1978.00500350045009
PMID:718472
Abstract

Motor nerve conduction velocity (MNCV) was measured in three peripheral nerves in each of 24 patients with myotonic dystrophy having various degress of associated glucose intolerance and was compared with results in a control group. Both groups had similar glucose tolerance and were matched for age and adiposity. The mean MNCV in the ulnar, median, and peroneal nerves in the myotonic dystrophy group were all significantly slowed (P less than .01). This peripheral nerve dysfunction, usually subclinical, is yet another manifestation of this multisystem disease and is unrelated to the associated glucose intolerance.

摘要

对24例伴有不同程度糖耐量异常的强直性肌营养不良患者的三条外周神经进行运动神经传导速度(MNCV)测量,并与对照组结果进行比较。两组糖耐量相似,且在年龄和肥胖程度上相匹配。强直性肌营养不良组尺神经、正中神经和腓总神经的平均MNCV均显著减慢(P<0.01)。这种通常为亚临床状态的外周神经功能障碍是这种多系统疾病的又一表现,且与伴发的糖耐量异常无关。

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