Ascorbate therapy in impaired neutrophil and monocyte chemotaxis. With atopy, hyperimmunoglobulinemia E, and recurrent infection.
作者信息
Foster C S, Goetzl E J
出版信息
Arch Ophthalmol. 1978 Nov;96(11):2069-72. doi: 10.1001/archopht.1978.03910060457014.
Abstract
A Candida albicans corneal ulcer developed in a 24-year-old man with a history of eczema, asthma, and multiple bacterial infections since childhood. The infection responded well to oral flucytosine (12 g/day for 15 days) and topical amphotericin B. Positive laboratory findings included eosinophilla, hyperimmunoglobulinemia E, and impaired neutrophil and monocyte spontaneous migration and chemotactic responses. Ascorbic acid corrected the monocyte defect in vitro and in vivo, but had no effect on neutrophil function.
摘要
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引用本文的文献
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[The Buckley syndrome: recurring, severe staphylococcal infections, eczema and hyperimmunoglobulinemia E. (author's transl)].[巴克利综合征：复发性严重葡萄球菌感染、湿疹和高免疫球蛋白E血症。（作者译）]
Infection. 1980;8 Suppl 3:248-54. doi: 10.1007/BF01639590.
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