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大羚羊(南非大羚羊)狂犬病的非咬伤传播

Non-bite transmission of rabies in kudu (Tragelaphus strepsiceros).

作者信息

Barnard B J, Hassel R H, Geyer H J, De Koker W C

出版信息

Onderstepoort J Vet Res. 1982 Dec;49(4):191-2.

PMID:7185035
Abstract

The titres of rabies virus in the saliva of kudu are higher than those of the salivary glands. The high titres are an indication of active excretion and multiplication in tissues other than the salivary glands. Two out of 4 kudu died of rabies after experimental infection by the instillation of infected saliva onto their buccal and nasal mucosae. Mice and 2 cattle resisted a similar exposure. Kudu also developed antibodies against rabies after instillation of HEP Flury virus onto their nasal and buccal mucosae. Cattle did not react when they were treated in the same way. These results suggest a high susceptibility of kudu to rabies when the virus is applied to their mucous membranes.

摘要

捻角羚唾液中的狂犬病毒滴度高于其唾液腺中的滴度。高滴度表明在唾液腺以外的组织中有活跃的排泄和增殖。4只捻角羚中有2只在通过将感染的唾液滴注到它们的颊部和鼻粘膜上进行实验性感染后死于狂犬病。小鼠和2头牛对类似的暴露有抵抗力。将HEP弗勒里病毒滴注到捻角羚的鼻和颊粘膜上后,它们也产生了抗狂犬病抗体。牛以同样方式处理时没有反应。这些结果表明,当病毒应用于捻角羚的粘膜时,它们对狂犬病高度易感。

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