组蛋白在由苯丙氨酰腺苷酸形成肽过程中的催化机制。
Catalytic mechanism of histone in peptide formation from phenylalanyl adenylate.
作者信息
Yamamoto N, Ishigami M, Kinjo M
出版信息
Orig Life. 1982 Dec;12(4):355-9. doi: 10.1007/BF00927067.
PMID:7185044
Abstract
Catalytic action of histone on peptide formation from phenylalanyl adenylate was studied. A peptide bond formation from phenylalanyl adenylate releases two protons. The proton release was increased in the presence of histone at a higher concentration. The catalytic action seems to be due to basic circumstance induced by histone, since (1) basic condition enhanced the proton release; (2) basic amino acid did not enhance the proton release.
摘要
研究了组蛋白对苯丙氨酰腺苷酸形成肽的催化作用。苯丙氨酰腺苷酸形成肽键会释放两个质子。在较高浓度组蛋白存在的情况下，质子释放增加。这种催化作用似乎是由于组蛋白诱导的碱性环境所致，因为：（1）碱性条件增强了质子释放；（2）碱性氨基酸并未增强质子释放。
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