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多核苷酸和一种碱性蛋白质对苯丙氨酰腺苷酸缩合的影响。

Effect of polynucleotides and a basic protein on the condensation of phenylalanyl adenylate.

作者信息

Ishigami M, Tonotsuka-Ohta N, Nagano K, Kinjo M

出版信息

Orig Life. 1980 Sep;10(3):293-9. doi: 10.1007/BF00928407.

DOI:10.1007/BF00928407
PMID:7191079
Abstract

The effect of polyuridylate and of histone on the oligomerization of phenylalanyl adenylate was tested. Polyuridylate which pairs with adenine under suitable conditions showed no effect. Histone increased the rate of the polymerization whereas a neutral protein, albumin, had no effect. Simultaneous presence of nucleotides diminished the effect of histone. The implication of these results on the prebiotic polypeptide formation is discussed.

摘要

测试了聚尿苷酸和组蛋白对苯丙氨酰腺苷酸寡聚化的影响。在合适条件下与腺嘌呤配对的聚尿苷酸没有显示出影响。组蛋白提高了聚合速率，而中性蛋白质白蛋白则没有影响。核苷酸的同时存在减弱了组蛋白的作用。讨论了这些结果对生命起源前多肽形成的意义。

相似文献

1
Effect of polynucleotides and a basic protein on the condensation of phenylalanyl adenylate.多核苷酸和一种碱性蛋白质对苯丙氨酰腺苷酸缩合的影响。
Orig Life. 1980 Sep;10(3):293-9. doi: 10.1007/BF00928407.
2
Catalytic mechanism of histone in peptide formation from phenylalanyl adenylate.组蛋白在由苯丙氨酰腺苷酸形成肽过程中的催化机制。
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引用本文的文献

1
Catalytic mechanism of histone in peptide formation from phenylalanyl adenylate.组蛋白在由苯丙氨酰腺苷酸形成肽过程中的催化机制。
Orig Life. 1982 Dec;12(4):355-9. doi: 10.1007/BF00927067.
2
Experimental studies related to the origin of the genetic code and the process of protein synthesis--a review.关于遗传密码起源和蛋白质合成过程的实验研究——综述
Orig Life. 1983 Mar;13(1):3-42. doi: 10.1007/BF00928761.

本文引用的文献

1
[A SPECTROPHOTOMETRIC METHOD PERMITTING SEPARATE STUDY OF DOUBLE AND TRIPLE HELIX COMPLEXES FORMED BY POLYRIBOADENYLIC AND POLYRIBOURIDYLIC ACID].
C R Hebd Seances Acad Sci. 1964 Nov 2;259:3104-7.
2
The chemical synthesis of amino acyladenylates.氨酰腺苷酸的化学合成。
J Biol Chem. 1958 Sep;233(3):608-11.
3
Physicochemical basis of the recognition process in nucleic acid interactions. I. Interactions of polyuridylic acid and nucleosides.
J Mol Biol. 1966 Apr;16(2):523-43. doi: 10.1016/s0022-2836(66)80189-4.
4
The binding of basic proteinoids with organismic or thermally synthesized polynucleotides.碱性类蛋白质与生物合成或热合成多核苷酸的结合。
Biochim Biophys Acta. 1968 Jun 26;160(2):239-45. doi: 10.1016/0005-2795(68)90092-5.
5
Specificity of oligonucleotide synthesis directed by polyuridylic acid.由聚尿苷酸指导的寡核苷酸合成的特异性
Proc Natl Acad Sci U S A. 1968 Jun;60(2):409-15. doi: 10.1073/pnas.60.2.409.
6
Nonenzymatic synthesis of oligoadenylates on a polyuridylic acid template.在聚尿苷酸模板上进行寡聚腺苷酸的非酶促合成。
Proc Natl Acad Sci U S A. 1968 Mar;59(3):726-33. doi: 10.1073/pnas.59.3.726.
7
Selective condensation of aminoacyl adenylates by nucleoproteinoid microparticles (prebiotic-lysine-model system-genetic code).通过类核蛋白微粒（益生元赖氨酸模型系统 - 遗传密码）对氨酰腺苷酸进行选择性缩合。
Proc Natl Acad Sci U S A. 1972 Jan;69(1):106-8. doi: 10.1073/pnas.69.1.106.
8
The origin of the genetic code.遗传密码的起源。
Orig Life. 1975 Oct;6(4):551-60. doi: 10.1007/BF00928903.