Nagy J, Brasch H, Trinn C, Burger T
Acta Med Acad Sci Hung. 1982;39(3-4):201-10.
A review of the clinical features, laboratory findings and course in 50 cases of IgA glomerulonephritis confirmed by biopsy is presented. The onset and clinical course of the process was oligosymptomatic in the majority of the cases with a predominance of microhematuria and persistent proteinuria. By the end of the observation period more than 50 per cent of the patients became hypertensive and in 16 cases serum creatinine levels attained 132 mumol/l (1.5 mg per 100 ml) or more. Proteinuria in excess of 1 g/24h, hypertension and an impaired concentration capacity at the onset heralded early progression.
本文报告了50例经活检确诊的IgA肾小球肾炎患者的临床特征、实验室检查结果及病程。在大多数病例中，该疾病的起病和临床过程症状不明显，以镜下血尿和持续性蛋白尿为主。到观察期末，超过50%的患者出现高血压，16例患者血清肌酐水平达到132μmol/l（每100ml1.5mg）或更高。起病时蛋白尿超过1g/24小时、高血压和浓缩功能受损预示着疾病早期进展。
