Dubini M
G Ital Med Lav. 1982 Jul-Sep;4(4-5):227-30.
The human carcinogenic activity of 4-4' amino diphenyl and 2 amino naphthalene, drew occupational physician's attention to "aromatic amines" as potentially carcinogenic compounds. The chemical-physical and biological properties of groups of products with structure very similar to them, show that the expression "aromatic amines" cannot define a class of compounds, but that it is necessary to consider only individual substances. The solutions carried out in industry for the replacement of some human cancerogenic products are reported.
4,4'-二氨基联苯和2-氨基萘的人类致癌活性,使职业医师将注意力投向“芳香胺”这类潜在的致癌化合物。与它们结构非常相似的几组产品的化学物理和生物学特性表明,“芳香胺”这一表述并不能定义一类化合物,而只需考虑个别物质。本文报道了工业上为替代某些人类致癌产品而采取的解决办法。