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酒精对听反射松弛指数的影响。

The effects of alcohol on the acoustic Reflex Relaxation Index.

作者信息

Robinette M S, Alper R R, Brey R H

出版信息

J Aud Res. 1981 Oct;21(3):159-65.

PMID:7185810
Abstract

Normal-hearing young adults (6 M, 5 F) ingested 1.5 ml alcohol per Kg body weight over 90 min (blood alcohol level then being 0.104 +/- 0.016%), then tested for contralateral acoustic reflex (AR) threshold using an otoadmittance meter, and given the acoustic Reflex Relaxation Index (RRI) test of Norris, Stelmachowicz and Taylor. Each stimulus for the RRI was a 4-sec train of pulses at a level 10 db above AR threshold at .5, 1, or 2 kc/s, with equivalent on-time of 166.7 msec and off-time of 200 msec. AR responses were displayed on an X-Y recorder. RRI was taken as the percentage of total relation of the AR during off-times. The AR relaxed relatively more during off-times, and the RRI consequently significantly increased, in the alcohol vs the control condition, mean differences in RRI score in percent being 5.0, 12,9, and 21.3% for .5, 1, and 2 kc/s, respectively. Group mean RRI at all 3 frequencies under alcohol was close to the cut-off score suggested as "normal" by the test originators, but in 6 of the 11 Ss RRI interpretation by that criterion changed from "normal" to "not normal" under alcohol at one or more frequencies. There are unresolved differences in the effect of specific temporal stimulus patterning on RRI. Caution is recommended in interpreting RRI in the clinic as suggestive of sensorineural hearing impairment if S is at the time under the influence of a CNS depressant.

摘要

听力正常的年轻成年人(6名男性,5名女性)在90分钟内每千克体重摄入1.5毫升酒精(此时血液酒精浓度为0.104±0.016%),然后使用耳声导抗仪测试对侧听觉反射(AR)阈值,并进行诺里斯、斯特尔马乔维茨和泰勒的听觉反射松弛指数(RRI)测试。RRI的每个刺激是在0.5、1或2千赫兹时比AR阈值高10分贝的4秒脉冲序列,等效开启时间为166.7毫秒,关闭时间为200毫秒。AR反应显示在X-Y记录仪上。RRI被视为关闭时间内AR总松弛的百分比。与对照条件相比,在酒精作用下,AR在关闭时间内相对松弛得更多,因此RRI显著增加,对于0.5、1和2千赫兹,RRI得分的平均差异百分比分别为5.0%、12.9%和21.3%。在酒精作用下,所有3个频率的组平均RRI接近测试发起者建议作为“正常”的临界分数,但在11名受试者中的6名中,根据该标准,RRI在一个或多个频率下在酒精作用下从“正常”变为“不正常”。特定时间刺激模式对RRI的影响存在未解决的差异。如果受试者当时受到中枢神经系统抑制剂的影响,建议在临床解释RRI时谨慎,因为它可能提示感音神经性听力障碍。

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