通过仓鼠颊囊吸收氟化物：一个依赖于pH值的过程。

Fluoride absorption through the hamster cheek pouch: a pH-dependent event.

作者信息

Whitford G M, Callan R S, Wang H S

出版信息

J Appl Toxicol. 1982 Dec;2(6):303-6. doi: 10.1002/jat.2550020608.

DOI:10.1002/jat.2550020608

Abstract

The fractional absorptions of fluoride, 3H2O, 125I and 14C-DMO from the hamster cheek pouch were determined as functions of solution pH. When the pH was less than 5, fluoride absorption rate was inversely related to pH. The absorption rates of the other substances were not influenced by pH. The fractional absorptions of fluoride and 3H2O were independent of fluoride concentrations over the range 1-53 mM. The data indicate that the absorption of fluoride through this keratinized epithelium occurs mainly by the diffusion of non-ionic HF.

摘要

测定了氟化物、3H2O、125I和14C - DMO从小仓鼠颊囊的分数吸收作为溶液pH值的函数。当pH值小于5时，氟化物吸收速率与pH值呈负相关。其他物质的吸收速率不受pH值影响。氟化物和3H2O的分数吸收在1 - 53 mM范围内与氟化物浓度无关。数据表明，氟化物通过这种角化上皮的吸收主要通过非离子型HF的扩散发生。