Ono Y, Tanimoto T, Kohata T, Arakaki Y, Takanashi S, Takahashi O, Kamiya T, Nishimura T, Kozuka T, Naitoh Y
J Cardiogr. 1982 Dec;12(4):1009-21.
Thallium-201 myocardial imaging was performed in 21 patients with transposition of the great arteries (TGA). Thirteen patients were studied before operation, eight patients after Mustard operation and five patients after Rastelli operation. Five patients were studied sequentially before and after the surgery. Each image was compared with hemodynamic and angiographic findings in order to assess the usefulness of this method. In the 13 patients with preoperative TGA, it was possible to differentiate TGA with the intact ventricular septum from TGA with associated anomalies such as patent ductus arteriosus or ventricular septal defect, and also TGA with pulmonary hypertension or pulmonary stenosis from TGA without them by evaluating the degree of thallium uptake in the free wall of the pulmonary ventricle (anatomical left ventricle). The degree of thallium uptake was well correlated with systolic pressure of the pulmonary ventricle (r = 0.98). In the 13 patients with postoperative TGA, it was less correlated with the pulmonary ventricular systolic pressure (r = 0.83). Four cases sequentially studied showed a marked decrease in thallium uptake in the pulmonary ventricle 10 to 16 months after Rastelli operation. But the corrected thallium uptake (thallium activity/ventricular systolic pressure) was more increased compared with the uptake of the systemic ventricle after the surgery. This was probably related to a decrease of the pressure load to the pulmonary ventricle following the surgery and to the fact that there should be some delay of a decrease of the ventricular mass. An increased lung uptake of thallium was noted in the cases of tricuspid regurgitation after Mustard operation, but the degree of regurgitation was not clearly correlated with the increase of thallium uptake in the lung. In five cases after Rastelli operation, one patient showed a high degree of thallium uptake of the pulmonary ventricle (anatomical right ventricle), and the conduit valve calcification and severe pulmonary stenosis were confirmed by cardiac catheterization and angiography. Thus myocardial imaging provides a reliable mean for the qualitative and quantitative assessment of TGA before and after operation.
对21例大动脉转位(TGA)患者进行了铊-201心肌显像。13例患者在手术前接受研究,8例患者在Mustard手术后接受研究,5例患者在Rastelli手术后接受研究。5例患者在手术前后进行了连续研究。将每幅图像与血流动力学和血管造影结果进行比较,以评估该方法的实用性。在13例术前TGA患者中,通过评估肺心室(解剖学左心室)游离壁的铊摄取程度,可以将室间隔完整的TGA与伴有动脉导管未闭或室间隔缺损等相关异常的TGA区分开来,也可以将伴有肺动脉高压或肺动脉狭窄的TGA与不伴有这些情况的TGA区分开来。铊摄取程度与肺心室收缩压密切相关(r = 0.98)。在13例术后TGA患者中,其与肺心室收缩压的相关性较低(r = 0.83)。4例连续研究的病例显示,Rastelli手术后10至16个月,肺心室的铊摄取明显减少。但校正后的铊摄取(铊活性/心室收缩压)与术后体心室的摄取相比增加得更多。这可能与手术后肺心室压力负荷的降低以及心室质量减少存在一定延迟有关。在Mustard手术后三尖瓣反流的病例中,发现肺内铊摄取增加,但反流程度与肺内铊摄取增加之间没有明显相关性。在5例Rastelli手术后的病例中,1例患者肺心室(解剖学右心室)的铊摄取程度较高,心脏导管检查和血管造影证实存在导管瓣膜钙化和严重肺动脉狭窄。因此,心肌显像为术前和术后TGA的定性和定量评估提供了可靠的手段。