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1
Unstable angina, myocardial infarction, heparin and death: medium dose heparin (not exceeding 20,000 units/day) in the treatment of patients with acute coronary event--first year and long-term comparative mortality.不稳定型心绞痛、心肌梗死、肝素与死亡：中等剂量肝素（不超过20000单位/天）治疗急性冠状动脉事件患者——首年及长期比较死亡率
Trans Am Clin Climatol Assoc. 1983;94:141-53.
2
Activated partial thromboplastin time and clinical outcome after thrombin inhibition in unstable coronary artery disease.不稳定型冠状动脉疾病中凝血酶抑制后活化部分凝血活酶时间与临床结局
Eur Heart J. 1999 Nov;20(22):1657-66. doi: 10.1053/euhj.1999.1750.
3
[Analgesic action of subcutaneous heparin therapy of stenocardia].[皮下注射肝素治疗心绞痛的镇痛作用]
Clin Ter. 1972 Aug 15;62(3):225-38.
4
Effectiveness of anticoagulants.抗凝剂的有效性。
Semin Thromb Hemost. 1986 Jan;12(1):21-37. doi: 10.1055/s-2007-1003532.
5
Long-term low-molecular-mass heparin in unstable coronary-artery disease: FRISC II prospective randomised multicentre study. FRagmin and Fast Revascularisation during InStability in Coronary artery disease. Investigators.
Lancet. 1999 Aug 28;354(9180):701-7.
6
A comparison of low-molecular-weight heparin with unfractionated heparin for unstable coronary artery disease. Efficacy and Safety of Subcutaneous Enoxaparin in Non-Q-Wave Coronary Events Study Group.低分子量肝素与普通肝素治疗不稳定型冠状动脉疾病的比较。皮下注射依诺肝素治疗非Q波冠状动脉事件研究组的疗效与安全性。
N Engl J Med. 1997 Aug 14;337(7):447-52. doi: 10.1056/NEJM199708143370702.
7
[The role of low-molecular-weight heparin in unstable angina, acute myocardial infarction and post-elective percutaneous transluminal coronary angioplasty].低分子量肝素在不稳定型心绞痛、急性心肌梗死及择期经皮腔内冠状动脉成形术后的作用
Arq Bras Cardiol. 1995 Dec;65(6):475-8.
8
[Comparison of low-molecular-weight heparin and unfractionated heparin in the treatment of unstable angina].低分子量肝素与普通肝素治疗不稳定型心绞痛的比较
Rev Med Chil. 1998 Mar;126(3):259-64.
9
Short-term (28 days) prognosis between genders according to the type of coronary event (Q-wave versus non-Q-wave acute myocardial infarction versus unstable angina pectoris).根据冠状动脉事件类型（Q波与非Q波急性心肌梗死与不稳定型心绞痛）划分的不同性别短期（28天）预后情况。
Am J Cardiol. 2004 Nov 1;94(9):1161-5. doi: 10.1016/j.amjcard.2004.07.084.
10
[Heparin therapy in coronary disease].[冠状动脉疾病中的肝素治疗]
Dtsch Med Wochenschr. 1992 Jan 3;117(1):35-6.

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1
Heparan sulfate proteoglycans present PCSK9 to the LDL receptor.硫酸乙酰肝素蛋白聚糖将前蛋白转化酶枯草溶菌素9呈递给低密度脂蛋白受体。
Nat Commun. 2017 Sep 11;8(1):503. doi: 10.1038/s41467-017-00568-7.
2
Heparin versus placebo for non-ST elevation acute coronary syndromes.肝素与安慰剂治疗非ST段抬高型急性冠脉综合征的比较
Cochrane Database Syst Rev. 2014 Jun 27;2014(6):CD003462. doi: 10.1002/14651858.CD003462.pub3.
3
Heparin for oral use: preliminary studies.口服肝素：初步研究。
Trans Am Clin Climatol Assoc. 1993;104:94-102; discussion 102-3.

本文引用的文献

1
PHYSIOLOGIC ACTIONS OF HEPARIN NOT RELATED TO BLOOD CLOTTING.肝素与血液凝固无关的生理作用。
Am J Cardiol. 1964 Jul;14:18-24. doi: 10.1016/0002-9149(64)90099-2.
2
Initial myocardial infarction among 503 veterans: five-year survival.
Am J Med. 1960 Jun;28:871-83. doi: 10.1016/0002-9343(60)90196-0.
3
Heparin versus heparin-bishydroxycoumarin anticoagulant therapy: comparison in patients with acute complicated myocardial infarction.肝素与肝素-双香豆素抗凝治疗：急性复杂性心肌梗死患者的比较
JAMA. 1960 Oct 29;174:1157-60. doi: 10.1001/jama.1960.03030090013003.
4
Effect of heparin on lipemia-induced angina pectoris.肝素对脂血症诱发心绞痛的作用。
J Am Med Assoc. 1957 Mar 2;163(9):727-31. doi: 10.1001/jama.1957.02970440023007.
5
Inhibition of rat arterial smooth muscle cell proliferation by heparin. In vivo studies with anticoagulant and nonanticoagulant heparin.肝素对大鼠动脉平滑肌细胞增殖的抑制作用。抗凝肝素与非抗凝肝素的体内研究。
Circ Res. 1980 May;46(5):625-34. doi: 10.1161/01.res.46.5.625.
6
Cultured endothelial cells produce a heparinlike inhibitor of smooth muscle cell growth.培养的内皮细胞产生一种平滑肌细胞生长的类肝素抑制剂。
J Cell Biol. 1981 Aug;90(2):372-9. doi: 10.1083/jcb.90.2.372.
7
Heparin necrosis: an anticoagulant-induced cutaneous infarct.肝素性坏死：一种抗凝剂诱导的皮肤梗死。
J Am Acad Dermatol. 1982 Nov;7(5):674-7. doi: 10.1016/s0190-9622(82)70150-1.
8
Heparin effect on blood viscosity.肝素对血液粘度的影响。
Clin Cardiol. 1982 Mar;5(3):215-8. doi: 10.1002/clc.4960050303.
9
Adjusted subcutaneous heparin versus warfarin sodium in the long-term treatment of venous thrombosis.皮下注射调整剂量肝素与华法林钠在静脉血栓形成长期治疗中的比较
N Engl J Med. 1982 Jan 28;306(4):189-94. doi: 10.1056/NEJM198201283060401.
10
Heparin-induced hypoaldosteronism. Report of a case.
JAMA. 1981 Nov 13;246(19):2189-90.

Unstable angina, myocardial infarction, heparin and death: medium dose heparin (not exceeding 20,000 units/day) in the treatment of patients with acute coronary event--first year and long-term comparative mortality.

作者信息

Sayen J J, Singer R B, Peirce G, Horwitz O

出版信息

Trans Am Clin Climatol Assoc. 1983;94:141-53.

PMID:7186227
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2279570/
Abstract
摘要