Giachino G M, Perrelli G, Passarino G, Comino E, Pira E, Scansetti G, Rubino G F
G Ital Med Lav. 1982 Nov;4(6):263-5.
An experimental research was carried out at the Institute of Occupational Health of Turin University on the risks following exposure to oligomers with particular reference to the textile industry. A group of 36 Sprague-Dawley rats were injected endotracheally with a suspension of dust collected from various sections of twisting and spinning departments while 6 rats used a referent groups, were treated with normal solution in the way. Five rats had pneumonia and 1 rat showed the presence of aspecific granuloma whereas the histological patterns for the other rats were found to be similar to those of the control group. In the Authors' opinion it is impossible at the moment, to give a definite conclusion as to the role of oligomers in lung damage.
都灵大学职业健康研究所针对接触低聚物后的风险开展了一项实验研究,特别关注纺织行业。一组36只斯普拉格-道利大鼠经气管内注射从捻线和纺纱部门各区域收集的粉尘悬浮液,而作为参照组的6只大鼠则以同样方式用生理盐水处理。5只大鼠患肺炎,1只大鼠出现非特异性肉芽肿,而其他大鼠的组织学模式与对照组相似。作者认为,目前无法就低聚物在肺部损伤中的作用给出明确结论。