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对人眼晶状体的差示扫描量热法测量

Differential scanning calorimetric measurements on human lenses.

作者信息

Bettelheim F A, Christian S, Lee L K

出版信息

Curr Eye Res. 1982;2(12):803-8. doi: 10.3109/02713688209020015.

DOI:10.3109/02713688209020015
PMID:7187637
Abstract

Differential scanning calorimetric measurements were performed between - 30 degrees C and 15 degrees C. The cortical sections of normal human lenses usually show one endotherm at the melting point, while the nucleus indicates a composite endotherm that can be separated into two endotherms with two melting points. Cataractous human lenses usually have composite endotherms from the cortical, intermediate as well as nuclear regions. We interpret the different endotherms as representing different kinds of freezable water contents: free water and partially bound water. Both in normal and cataractous human lenses, there is an appreciable amount of non-freezable water. The amount of non-freezable water is less in cataractous lenses than in normal lenses, indicating a syneretic process as a cause of cataract formation.

摘要

在-30℃至15℃之间进行差示扫描量热测量。正常人类晶状体的皮质部分通常在熔点处显示一个吸热峰,而晶状体核则显示一个复合吸热峰,该复合吸热峰可分为两个具有两个熔点的吸热峰。白内障患者的晶状体通常在皮质、中间区域以及核区域都有复合吸热峰。我们将不同的吸热峰解释为代表不同类型的可冻结水含量:自由水和部分结合水。在正常和白内障患者的晶状体中,都存在相当数量的不可冻结水。白内障晶状体中不可冻结水的量比正常晶状体中的少,这表明脱水收缩过程是白内障形成的一个原因。

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