Stewart A, Augusteyn R C
Exp Eye Res. 1984 Sep;39(3):307-15. doi: 10.1016/0014-4835(84)90018-6.
The levels of NAD+, NADH, NADP+ and NADPH have been determined in each cortex and nucleus of about 80 normal and cataractous human lenses and in a small number of calf, rabbit and rat lenses. Cataractous lenses had lower levels of all nucleotides than the normal lenses but no progressive decreases were associated with the development of nuclear colour, or with cortical, diabetic, traumatic and steroid cataracts. It was concluded that a lack of reduced pyridine nucleotides was not responsible for a decrease in the ability of the lens to protect itself against oxidative damage.
已测定约80个正常和白内障人晶状体的每个皮质和核以及少量小牛、兔子和大鼠晶状体中NAD+、NADH、NADP+和NADPH的水平。白内障晶状体中所有核苷酸的水平均低于正常晶状体，但核颜色的发展、皮质性、糖尿病性、外伤性和类固醇性白内障均未出现逐渐降低的情况。得出的结论是，缺乏还原型吡啶核苷酸并非晶状体保护自身免受氧化损伤能力下降的原因。
