左聚糖对结核菌素反应的影响

Shezen E, Leibovici J, Wolman M

Br J Exp Pathol. 1978 Oct;59(5):454-8.

High molecular levan (polyfructoside) inhibits the skin tuberculin reaction in guinea pigs as judged by the degree of induration and erythema. The effect is dose-dependent. No effect on cellular infiltration was observed in histological studies. The lymph nodes of levan-treated animals were smaller and exhibited a much milder granulomatous reaction than those of non-treated animals.

通过硬结程度和红斑判断，高分子量左聚糖（多聚果糖）可抑制豚鼠的皮肤结核菌素反应。该作用呈剂量依赖性。组织学研究未观察到对细胞浸润的影响。与未治疗动物相比，左聚糖治疗动物的淋巴结更小，肉芽肿反应也更轻。