Synder B D, Loewenson R B, Gumnit R J, Hauser W A, Leppik I E, Ramirez-Lassepas M
Neurology. 1980 Jan;30(1):52-8. doi: 10.1212/wnl.30.1.52.
Sixty-three patients with isolated global anoxic-ischemic injury were prospectively evaluated after cardiopulmonary arrest (CPA); 25 (40%) survived, 16 to an excellent recovery, 8 to a good recovery, and 1 with severe deficits. Forty-six percent of the patients achieved full alertness, and only patients who did so survived. Seventy-five percent of patients arousable or initially alert (level of consciousness [LOC] greater than or equal to 4) survived, all but two with excellent outcomes. Twenty-eight percent of patients initially in deep coma (LOC less than or equal to 3) survived, all with excellent or good outcomes. Ninety percent of patients who became fully alert did so within 72 hours. The likelihood of alerting is correlated with the LOC at given intervals after CPA. Reliable predictions of survival and outcome can often be based upon LOC alone within 2 days after CPA.
对63例心脏骤停（CPA）后出现孤立性全脑缺氧缺血性损伤的患者进行了前瞻性评估；25例（40%）存活，其中16例恢复良好，8例恢复较好，1例有严重缺陷。46%的患者实现了完全清醒，只有实现完全清醒的患者存活。75%可唤醒或最初清醒（意识水平[LOC]大于或等于4）的患者存活，除2例以外均恢复良好。28%最初处于深昏迷（LOC小于或等于3）的患者存活，均恢复良好或较好。90%完全清醒的患者在72小时内实现了清醒。唤醒的可能性与CPA后特定时间间隔的LOC相关。在CPA后2天内，通常仅根据LOC就可以对存活和预后进行可靠预测。
