同步辐射在肌肉收缩过程中肌球蛋白层线反射的时间分辨X射线衍射研究中的应用。

The use of synchrotron radiation in time-resolved X-ray diffraction studies of myosin layer-line reflections during muscle contraction.

作者信息

Huxley H E, Faruqi A R, Bordas J, Koch M H, Milch J R

出版信息

Nature. 1980 Mar 13;284(5752):140-3. doi: 10.1038/284140a0.

Abstract

Experiments on striated muscle have been carried out at the EMBL Outstation at DESY, Hamburg, using the electron-positron storage ring DORIS as a high-intensity X-ray source. The low-angle reflections from the myosin cross-bridges could be recorded more than 1,000 times more rapidly than with the best conventional X-ray sources, and could be followed during contraction with a time resolution of 10 ms.

摘要

在汉堡 DESY 的欧洲分子生物学实验室分站，利用正电子-电子储存环 DORIS 作为高强度 X 射线源，对横纹肌进行了实验。来自肌球蛋白横桥的低角度反射记录速度比最好的传统 X 射线源快 1000 多倍，并且在收缩过程中可以以 10 毫秒的时间分辨率进行跟踪。