Wallach R C, Cohen C, Bruckner H, Kabakow B, Deppe G, Ratner L
Obstet Gynecol. 1980 Mar;55(3):371-2. doi: 10.1097/00006250-198003000-00020.
Forty-six patients with recurrent disseminated ovarian carcinoma were treated with a combination of cis-dichlorodiammine platinum II (DDP) 50 mg/m2 and adriamycin 50 mg/m2 given intravenously every 3 weeks. All patients had failed prior chemotherapy. The combination of adriamycin and DDP produced objective responses in 14 of 46 patients. Severe side effects were frequent, but no patient died as a result of treatment. Disease in 4 of 7 complete responders is currently in remission up to 4 years.
46例复发性播散性卵巢癌患者接受了顺式二氯二氨铂II（DDP）50mg/m²和阿霉素50mg/m²联合治疗，每3周静脉给药一次。所有患者先前的化疗均告失败。阿霉素与DDP联合用药使46例患者中的14例产生了客观反应。严重副作用很常见，但没有患者因治疗而死亡。7例完全缓解患者中有4例的疾病目前已缓解长达4年。
