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利用孕中期胎儿镜检查获取的胎儿血液进行子宫内亲子鉴定。

In utero paternity testing utilizing fetal blood obtained by midtrimester fetoscopy.

作者信息

Golbus M S, Stephens J D, Cann H M

出版信息

Am J Hum Genet. 1980 Jan;32(1):88-91.

Abstract

To evaluate paternity in a case where both rape and conjugal coitus had occurred close to the time of conception, fetoscopy with fetal blood sampling was performed at 20 weeks gestation. Detailed blood group typing of the wife, husband, and fetus, and the presence of a very long Y chromosome in the last two, indicated a 99.9% chance that the fetus was fathered by the husband and only a 0.1% chance that it was fathered by "some other male Caucasian." The couple elected to continue the pregnancy. Neonatal testing verified the prenatal findings.

摘要

为评估在受孕时间前后不久既发生了强奸又有婚内性交的情况下的亲子关系,在妊娠20周时进行了胎儿镜检查及胎儿采血。对妻子、丈夫和胎儿进行了详细的血型鉴定,后两者中存在一条非常长的Y染色体,这表明胎儿由丈夫亲生的可能性为99.9%,而由“其他某个白人男性”亲生的可能性仅为0.1%。这对夫妇选择继续妊娠。新生儿检测证实了产前检查结果。

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本文引用的文献

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[Does a probability of paternity exist?].[存在父系概率吗?]
Med Leg Dommage Corpor. 1971 Oct-Dec;4(4):348-50.
5
Further studies on the antenatal detection of sickle cell anemia and other hemoglobinopathies.
Adv Exp Med Biol. 1972;28:337-46. doi: 10.1007/978-1-4684-3222-0_27.
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Prenatal diagnosis of Duchenne's muscular dystrophy.杜氏肌营养不良症的产前诊断
N Engl J Med. 1977 Nov 3;297(18):968-73. doi: 10.1056/NEJM197711032971803.
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The use of fetal blood for the prenatal diagnosis of genetic defects.
Monogr Hum Genet. 1978;9:222-6. doi: 10.1159/000401640.

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