DeCherney A H, Kort H, Barney J B, DeVore G R
Fertil Steril. 1980 Apr;33(4):407-10.
The diagnostic value of hysterosalpingography remains unquestioned. Previous studies have suggested that patients who underwent hysterosalpingography with an oil-soluble contract medium (OSCM) rather than a water-soluble contrast medium (WSCM) had higher subsequent fertility rates. This study evaluated subsequent fertility rates in 339 patients who underwent hysterosalpingography in which OSCM or WSCM was used. All forms of infertility were included and over-all, pregnancy occurred in the WSCM group in 21 of 162 patients (13%), in the OSCM group in 51 of 177 patients (29%); these rates were significantly different (P less than 0.001), with the unexplained infertility group and the male factor infertility group showing the most significant difference. Adverse effects of OSCM hysterosalpingography were not corroborated. For this reason it is suggested that initially the patient undergo hysterosalpingography with WSCM. Once patency has been established, 3 ml of OSCM should be injected as a therapeutic modality to increase subsequent fertility.
子宫输卵管造影术的诊断价值毋庸置疑。先前的研究表明，接受油溶性造影剂（OSCM）而非水溶性造影剂（WSCM）子宫输卵管造影术的患者后续生育率更高。本研究评估了339例行子宫输卵管造影术（使用OSCM或WSCM）患者的后续生育率。纳入了所有类型的不孕症，总体而言，WSCM组162例患者中有21例（13%）妊娠，OSCM组177例患者中有51例（29%）妊娠；这些比率有显著差异（P小于0.001），其中不明原因不孕症组和男性因素不孕症组差异最为显著。未证实OSCM子宫输卵管造影术有不良反应。因此建议患者最初采用WSCM进行子宫输卵管造影术。一旦确定通畅，应注入3ml OSCM作为一种治疗方式以提高后续生育率。
