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咪康唑治疗外阴阴道念珠菌病:6天疗法与3天疗程的比较

Miconazole in the treatment of vulvovaginal candidiasis: comparison of a 6-day therapy and a 3-day treatment course.

作者信息

Van Leusden H A, Nuijten S T

出版信息

Eur J Obstet Gynecol Reprod Biol. 1980 Mar;10(3):203-11. doi: 10.1016/0028-2243(80)90061-1.

Abstract

In a double-blind trial, 119 patients showing symptoms of Candida vulvovaginitis were treated with either 200 mg miconazole once daily for 6 days (A) or 400 mg miconazole once daily for 3 days (B), inserted intravaginally by means of a Scherer capsule. The efficacy was evaluated in 54 patients. A mycological cure rate was obtained in 93% of 29 patients from group A and in 80% of 25 patients from group B. The difference between the two therapy regimens was statistically not significant. No side-effects were observed.

摘要

在一项双盲试验中,119名有念珠菌性外阴阴道炎症状的患者接受了以下两种治疗之一:A组为每日一次阴道内塞入200毫克咪康唑,共6天;B组为每日一次阴道内塞入400毫克咪康唑,共3天,均使用谢勒胶囊给药。对54名患者进行了疗效评估。A组29名患者中的93%以及B组25名患者中的80%实现了真菌学治愈。两种治疗方案之间的差异无统计学意义。未观察到副作用。

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