Knight T E, Robinson H M, Sina B
Arch Dermatol. 1980 Jun;116(6):683-6.
Angiosarcoma with initial involvement of the scalp is a rare, malignant neoplasm. We present the case of a 77-year-old woman in whom extensive scarring alopecia developed that was proved histologically to be due to angiosarcoma. She had a good initial response to treatment with electron-beam therapy, but after seven months, extensive nodules and indurated areas on the face beyond the borders of the radiation field developed. Subsequently, massive cervical adenopathy and metastases to the lungs, liver, and spleen developed. Angiosarcoma must be differentiated from other malignant blood vessel tumors and should be considered in the differential diagnosis of scarring alopecia of the scalp in elderly patients.
首发累及头皮的血管肉瘤是一种罕见的恶性肿瘤。我们报告了一例77岁女性患者，该患者出现广泛的瘢痕性脱发，组织学检查证实是由血管肉瘤引起的。她对电子束治疗有良好的初始反应，但七个月后，在放射野边界以外的面部出现了广泛的结节和硬结区域。随后，出现了大量颈部淋巴结肿大以及肺、肝和脾转移。血管肉瘤必须与其他恶性血管肿瘤相鉴别，在老年患者头皮瘢痕性脱发的鉴别诊断中应考虑到该病。
