Sabbah H N, Marzilli M, Stein P D
Am Heart J. 1980 Jul;100(1):77-80. doi: 10.1016/0002-8703(80)90281-1.
Intracardiac sound was measured in six dogs, four with left ventricular cavity obliteration induced by isoproterenol, and two with catheter entrapment. In left ventricular cavity obliteration, no murmur occurred within the left ventricle. Whenever a systolic murmur occurred, it was distal to the aortic valve. In entrapment, no murmur occurred within the left ventricle or distal to the aortic valve. Previous studies in patients with hypertrophic obstructive cardiomyopathy showed that the systolic murmur was of greatest intensity within the left ventricular outflow tract. Therefore, intracardiac phonocardiography may assist in differentiating these conditions which produce an intraventricular pressure gradient.
对6只犬进行了心内声音测量，其中4只因异丙肾上腺素导致左心室腔闭塞，2只因导管陷入。在左心室腔闭塞时，左心室内未出现杂音。每当出现收缩期杂音时，其位于主动脉瓣远端。在导管陷入时，左心室内或主动脉瓣远端均未出现杂音。先前对肥厚性梗阻性心肌病患者的研究表明，收缩期杂音在左心室流出道内强度最大。因此，心内心音图检查可能有助于鉴别这些产生心室内压力梯度的情况。
