King D F, Dore R K, Gilbert D J, Gurevitch A W, Hirose F M
Int J Dermatol. 1980 Apr;19(3):149-53. doi: 10.1111/j.1365-4362.1980.tb00283.x.
The distinctions between eosinophilic fascitis (Shulman's syndrome) and scleroderma may sometimes be unclear. We describe a patient with generalized morphea who also had peripheral blood eosinophilia, fibrosis and inflammation of fascia, and hyper-globulinemia, features usually attributed to Shulman's syndrome. The latter diagnosis should be restricted to those patients whose history, clinical and laboratory findings, and response to therapy closely resemble Shulman's original description. Scleroderma and eosinophilic fasciitis may represent slightly differing aspects of the same disease spectrum, with a similar immunologic pathogenesis.
嗜酸性筋膜炎（舒尔曼综合征）与硬皮病之间的区别有时可能并不明确。我们描述了一位患有泛发性硬斑病的患者，该患者同时伴有外周血嗜酸性粒细胞增多、筋膜纤维化和炎症以及高球蛋白血症，这些特征通常归因于舒尔曼综合征。后一种诊断应仅限于那些病史、临床和实验室检查结果以及对治疗的反应与舒尔曼最初描述非常相似的患者。硬皮病和嗜酸性筋膜炎可能代表同一疾病谱中略有不同的方面，具有相似的免疫发病机制。
