Wickens M P, Woo S, O'Malley B W, Gurdon J B
Nature. 1980 Jun 26;285(5767):628-34. doi: 10.1038/285628a0.
Ovalbumin is synthesized by Xenopus oocytes injected with a plasmid containing either the chicken chromosomal ovalbumin gene or a plasmid from which the 5' region of the chromosomal gene has been deleted. However, oocytes injected with a plasmid containing full-length ovalbumin cDNA do not synthesize ovalbumin, despite the fact that at least as much stable, ovalbumin-specific RNA is transcribed from the cDNA as from the chromosomal gene.
卵清蛋白是由注射了含有鸡染色体卵清蛋白基因的质粒或已缺失染色体基因5'区域的质粒的非洲爪蟾卵母细胞合成的。然而，注射了含有全长卵清蛋白cDNA的质粒的卵母细胞却不能合成卵清蛋白，尽管从该cDNA转录出的稳定的、卵清蛋白特异性RNA至少与从染色体基因转录出的一样多。
