Hydroxylation of benzo[a]pyrene and binding of (-)trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene metabolites to deoxyribonucleic acid catalyzed by purified forms of rabbit liver microsomal cytochrome P-450. Effect of 7,8-benzoflavone, butylated hydroxytoluene and ascorbic acid.
作者信息
Belvedere G, Miller H, Vatsis K P, Coon M J, Gelboin H V
出版信息
Biochem Pharmacol. 1980 Jun 15;29(12):1693-702. doi: 10.1016/0006-2952(80)90127-6.
PMID:7190824
Abstract
摘要
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Hydroxylation of benzo[a]pyrene and binding of (-)trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene metabolites to deoxyribonucleic acid catalyzed by purified forms of rabbit liver microsomal cytochrome P-450. Effect of 7,8-benzoflavone, butylated hydroxytoluene and ascorbic acid.
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