Shvets V N, Portugalov V V
Biull Eksp Biol Med. 1978 Nov;86(11):601-4.
The effect of distribution of injected colony-forming units (CFU) in the recipient's organism was studied. The distribution was assessed by the "sedimentation factor" (f) criterion. This factor was found by the number of colonies revealed on histological sections of the spleen and femoral bone marrow in comparison with the number of colonies visible on the surface of the spleen. Macroscopic count of the colonies on the spleen permits, to assess the f value both in the whole spleen volume and in the femoral bone marrow. In this case f value was independent of the character of CFU differentiation. f value could change depending on the physiological condition of CFU population. In irradiation of the bone marrow CFU in a dose of 200, 400 and 600 R f value in the spleen decreased in comparison with control, but remained unchanged in the bone marrow.
研究了注射的集落形成单位（CFU）在受体机体中的分布效应。通过“沉降因子”（f）标准评估分布情况。该因子通过脾脏和股骨骨髓组织切片上显示的集落数量与脾脏表面可见的集落数量相比较得出。对脾脏上的集落进行宏观计数，可以评估整个脾脏体积以及股骨骨髓中的f值。在这种情况下，f值与CFU分化的特性无关。f值可能会根据CFU群体的生理状态而变化。以200、400和600拉德的剂量照射骨髓CFU时，脾脏中的f值与对照组相比降低，但骨髓中的f值保持不变。
