Jequier A M, Crich J P
Arch Androl. 1980 Sep;5(2):215-9. doi: 10.3109/01485018008986318.
New Zealand White Rabbits were immunized with whole human semen and with its components. A positive Gel Agglutination Test (GAT) was present in the sera of these rabbits, whereas it was negative in rabbit sera from control immunizations. The GAT response was positive from all the sera from rabbits immunized with the components of seminal fluid whether or not sperm were present, demonstrating that the GAT response is not dependent on the formation of an antibody specific to spermatozoa. Treatment of the immunized sera with two immunoglobulin precipitating sera did not render these rabbit sera GAT negative. These data provide further evidence that the substance or substances producing a positive GAT response are not immunoglobulins.
用全人类精液及其成分对新西兰白兔进行免疫。这些兔子的血清中出现了阳性凝胶凝集试验（GAT），而对照免疫的兔血清中则为阴性。无论是否存在精子，用精液成分免疫的兔子的所有血清的GAT反应均为阳性，这表明GAT反应不依赖于针对精子的特异性抗体的形成。用两种免疫球蛋白沉淀血清处理免疫血清并没有使这些兔血清的GAT呈阴性。这些数据进一步证明，产生阳性GAT反应的一种或多种物质不是免疫球蛋白。
