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[大鼠在搭乘生物卫星“宇宙-782”飞行后对不同难度行为任务的反应]

[Reactions of rats to behavior tasks of different degrees of difficulty after flight aboard the biosatellite "cosmos-782"].

作者信息

Livshits N N, Meĭzerov E S, Apanasenko Z I, Kuznetsova M A

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1980 May-Jun;30(3):507-12.

PMID:7192031
Abstract

Maze behaviour of rats was studied on 6--25th days after exposure on biosatellite "Kosmos-782". Presentation of a foreign stimulus (a bell) on the 6--7th day after return, had a weaker effect on the maze performance in experimental rats, than in the control group. The experimental animals were also better adapted, as compared to the control ones, to an increased functional stress on CNS (increased number of runs in the maze from 3 to 16 in one session), applied on 11--13th day after the return. Similarly, the ability to use previous experience in a new situation, tested an 15--20th day after the return was slightly higher in experimental animals than in the control. During elaboration of a habit in an utterly new complex maze, first runs in each session were performed by experimental rats in the same way as by the control ones, whereas in second runs the afterflight rats did considerably worse than those in the control. The data analysis showed that the described changes in higher nervous activity were not caused by muscle weakness; they were due to exhaustion of the higher parts of CNS, while closing functions remained intact.

摘要

在生物卫星“宇宙-782”上暴露6至25天后,对大鼠的迷宫行为进行了研究。返回后第6至7天呈现外来刺激(铃声)时,与对照组相比,对实验大鼠迷宫表现的影响较弱。与对照组相比,实验动物对中枢神经系统功能应激增加(在一次实验中迷宫奔跑次数从3次增加到16次)也有更好的适应性,该应激施加于返回后的第11至13天。同样,返回后第15至20天测试的在新情境中运用先前经验的能力,实验动物略高于对照组。在全新复杂迷宫中形成习惯的过程中,实验大鼠在每次实验的首次奔跑中与对照组表现相同,而在第二次奔跑中,实验大鼠的表现比对照组差得多。数据分析表明,上述高级神经活动的变化并非由肌肉无力引起;它们是由于中枢神经系统高级部分的衰竭,而闭合功能保持完好。

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