人类ACO2、ARSA和NAGA基因在22号染色体上的区域定位。
Regional localization of the genes coding for human ACO2, ARSA, and NAGA on chromosome 22.
作者信息
Geurts van Kessel A H, Westerveld A, de Groot P G, Meera Khan P, Hagemeijer A
出版信息
Cytogenet Cell Genet. 1980;28(3):169-72. doi: 10.1159/000131527.
PMID:7192199
Abstract
The segregation of the chromosome 22 markers ACO2, ARSA, and NAGA was studied in somatic cell hybrid clones. These hybrids were isolated following fusion of Chinese hamster (E36 or a3) cells with leucocytes of donors carrying an (X;22) or (1;22) translocation. The results suggest the assignment of ARSA and NAGA to the region 22q13 leads to 22qter and of ACO2 to the region 22q11 leads to 22q13.
摘要
在体细胞杂交克隆中研究了22号染色体标记物ACO2、ARSA和NAGA的分离情况。这些杂种细胞是在中国仓鼠（E36或a3）细胞与携带（X；22）或（1；22）易位的供体白细胞融合后分离得到的。结果表明，ARSA和NAGA定位于22q13至22qter区域，ACO2定位于22q11至22q13区域。
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