双胞胎中的冠状动脉疾病
Coronary artery disease in twins.
作者信息
Holmes D R, Kennel A J, Smith H C, Gordon H, Moore S B
出版信息
Br Heart J. 1981 Feb;45(2):193-7. doi: 10.1136/hrt.45.2.193.
Abstract
In two pairs of monozygotic twins with coronary artery disease who were studied by coronary angiography, there were striking similarities in the clinical course, response to exercise, and distribution of coronary artery disease. Though it is difficult to distinguish between heredity as an independent risk factor and the other major risk factors, the similarities in each twin pair may be best explained by identical heredity.
摘要
在两对通过冠状动脉造影术进行研究的患有冠状动脉疾病的同卵双胞胎中，其临床病程、运动反应以及冠状动脉疾病的分布情况存在显著相似性。尽管很难区分遗传作为一个独立的风险因素与其他主要风险因素，但每对双胞胎中的相似性或许最好用相同的遗传来解释。
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