Philip J, Bang J
Br Med J. 1978 Oct 28;2(6146):1183-4. doi: 10.1136/bmj.2.6146.1183.
A consecutive series of 1177 pregnant women examined by amniocentesis for chromosomal abnormalities delivered 1039 live-born babies weighing over 2500 g and 79 live-born babies weighing under 2500 g. Twenty-six abortions were induced (2.2%)--13 (1.1%) because of chromosomal abnormalities--and 28 women (2.4%) aborted spontaneously; in these cases chromosomes were normal. Analysis of all spontaneous abortions in the series suggested that 0.3-0.7% might have resulted from amniocentesis.
对1177名孕妇进行羊膜穿刺术以检查染色体异常情况,她们共分娩出1039名体重超过2500克的活产婴儿和79名体重低于2500克的活产婴儿。引产26例(2.2%)——其中因染色体异常引产13例(1.1%)——自然流产28例(2.4%);这些自然流产病例的染色体均正常。对该系列所有自然流产病例的分析表明,其中0.3 - 0.7%可能是羊膜穿刺术所致。